Nidoqueen is a large, bipedal blue mammalian Pokémon with distinct reptilian features. Its body is encased with extremely hard scales that serve as excellent protection from any attack and stand up when Nidoqueen is excited or provoked. It has a blunt snout, narrow brown eyes, and large ears with brown insides. There is a small horn on its forehead, a single spine on each ear, and a line of toxic spikes running down its back. Each hand has three short claws and each foot has two claws. Its lower jaw, the front of its abdomen, and two plates on its chest are cream-colored. It has a thick, powerful tail. Nidoqueen is a female-only species.
Nidoqueen can be quite fierce and is very protective of its young. This Pokémon is at its strongest when it is defending its young, and it will try to seal the entrance to its burrow to protect them. It also places its young in the gaps between the spines on its back which never release poison when the children are present. Nidoqueen is more adept at being defensive than offensive. Nidoqueen's armor-like scales allow it to defend its children from any attack. When in contact with foes, it can poison them with the spikes on its back or cause small tremors by slamming the ground. It is also adept at sending foes flying with harsh tackles and it uses its hefty bulk to execute powerful moves. Being the result of an evolution via Evolution stone, Nidoqueen is rarely found in the wild. However, they can be found in savannas and plains.
Nidoqueen evolves from Nidorina and is the final form of Nidoran♀.
(For specifics on this Pokémon's evolution in the games, refer to Game data→Evolution data.)
Nidoqueen debuted in Mewtwo Strikes Back, under the ownership of Fergus. She was captured and cloned by Mewtwo. She also appeared in the remake Mewtwo Strikes Back—Evolution, where the exact same thing happened to her. The Nidoqueen clone was seen again in Mewtwo Returns, along with what appeared to be Nidoqueen babies, despite the fact that Nidoqueen cannot breed and her unevolved form is Nidoran♀.
Nidoqueen made her main series debut in Navel Maneuvers, under the ownership of Danny. She competed against Ash's Lapras in a challenge to freeze a super-heated geyser. Afterward, Nidoqueen helped Danny's Machoke and Scyther carve Danny's sled. She reappeared in flashbacks in A Way Off Day Off and Hello, Pummelo!.
In A Tent Situation, Gary Oak used a Nidoqueen to defend his grandfather's laboratory from Team Rocket. In Can't Beat the Heat!, Gary used Nidoqueen during his match against Ash in the Silver Conference. She defeated Tauros and was defeated by Snorlax.
In The Bicker the Better, Andi has a Nidoqueen, while her boyfriend Oscar has a Nidoking. They had a Double Battle with Ash and May, and due to Oscar and Andi's communication with each other, they were able to defeat Ash and May with relative ease.
In the original timeline of Arceus and the Jewel of Life, a hypnotized Damos commanded his four Nidoqueen to attack Arceus with Shock Wave. When Ash and his friends traveled to the past to prevent this, Marcus, the one responsible for hypnotizing Damos, managed to use the Nidoqueen again to attack Arceus.
In Pikachu's Vacation, a Nidoqueen was at the Pokémon Theme Park.
In The Power of One, a Nidoqueen sensed the disturbance caused by Lawrence III.
Multiple Nidoqueen appeared in Celebi: The Voice of the Forest.
A Nidoqueen appeared in Extreme Pokémon!, under the ownership of a participant in the Extreme Pokémon Race.
In Historical Mystery Tour!, Ash encountered a Nidoqueen in Xatu's Forest. In this episode, Nidoqueen was depicted with a blue jaw instead of a cream-colored one due to an error.
In A Performance Pop Quiz!, Queenko's Nidoqueen competed in the Anistar City Pokémon Showcase. In Master Class is in Session!, she competed in the Master Class Pokémon Showcase in Gloire City.
In I Choose You!, a Nidoqueen fell under the control of Marshadow.
A Nidoqueen appeared in This Could be the Start of Something Big!.
||Nidoqueen, the Drill Pokémon. Nidoqueen has thick skin covering its entire body, protecting it from whatever techniques are used against it.
In File 1: Red, a Nidoqueen was one of the Pokémon seen in Professor Oak's introduction.
Two Nidoqueen appeared in File 3: Giovanni. The first one was seen during the explanation of the Master Ball's capabilities, and the other was sent out by Giovanni to battle Red's Charizard at the Silph Co. building. She was able to defeat Charizard, allowing Giovanni to successfully retreat.
In The Show, a Nidoqueen briefly appeared under the ownership of a Trainer watching the Kimono Girls' performance in Ecruteak City.
A Nidoqueen appeared in Blossom's Dream.