Glameow is a gray feline Pokémon with a slender physique. It has a crescent-shaped head with two white-tipped ears. It also has a white muzzle, a small black nose, pink eyelids, yellow eyes with blue irises, and two rows of thin whiskers. Its neck has a ruff-like fringe, and its legs have similar fringes. Its feet are tipped with white and have pink paw pads on the underside. It has a curled, spring-shaped tail and a white fluff at the tip of it. It has sharp claws and a powerful tail. Its eyes are also capable of using hypnotic powers.
Glameow tends to be spiteful and fickle, having a tendency to hook its claws into the nose of its trainer if it's not fed. When it's happy, it demonstrates movements with its tail, like a dancing ribbon. As it has a domesticated quality, it tends to appear in urban areas.