Venomoth is a lepidopteran insect Pokémon whose body is varying shades of purple. Its head and thorax are both light purple, and it has bulbous, round, light blue eyes, a small mandible, and a three-point crest on its head. Tucked close to its thorax are three pairs of tiny, whitish legs. Its abdomen is paler with several black, zigzagging stripes encircling it. It has two pairs of pale purple moth-like wings with thin black venation.
Venomoth's wings are covered in dust-like scales that vary in color depending on their toxic capability. Dark scales are poisonous, while lighter scales can cause paralysis. These scales are released when Venomoth flutters its wings and leak out poison once they make contact with the skin. Venomoth lives in dense temperate forests with thick undergrowth and little light. As a nocturnal Pokémon, Venomoth comes out at night to hunt for its favorite prey. It prefers to feed on insects that gather around light sources, and Venomoth is attracted to bright lights itself. As stated in Pokémon Adventures, Venomoth has a short lifespan.
In Working My Way Back to Mew!, Goh caught a Venomoth. It has since made further appearances in Pokémon Journeys: The Series.
In The Ninja Poké-Showdown, after it evolved from Venonat, Koga used his Venomoth in a Gym battle against Ash, during which it battled Pidgeotto before the match was interrupted by Team Rocket.
In All Things Bright and Beautifly!, Chaz used a Venomoth during the Rustboro City Pokémon Contest. During the Contest, it was able to advance to the Battle Stage and reach the final round, where it went up against Janet's Beautifly. Although both Coordinators gave it everything they had, Janet managed to defeat Chaz and won herself the Rustboro Ribbon.
In Shocks and Bonds, Katie used a Venomoth during her battle with Ash during the Ever Grande Conference. Venomoth's Disable caused Torkoal to be unable to use Iron Defense, so that her Golduck could knock out the Coal Pokémon with Hydro Pump. In the following episode, it used Disable once again to prohibit Swellow from using Peck. Despite this, it was eventually defeated by Swellow.
A Venomoth appeared at the beginning of Mewtwo Strikes Back and its remake Mewtwo Strikes Back—Evolution, under the ownership of Raymond. Alongside two of his other Pokémon, it fought Ash's Pikachu, only for all of them to be defeated with Thunderbolt.
A Venomoth appeared in The Kangaskhan Kid.
In Round One - Begin!, a Trainer's Venomoth competed in the Indigo Plateau Conference.
In Friends to the End, Assunta used a Venomoth to battle Ritchie's Butterfree, nicknamed Happy.
In Tracey Gets Bugged, a Venomoth was on Murcott Island.
In Misty Meets Her Match, Rudy's Venomoth was at the Trovita Gym.
In The Power of One, multiple Venomoth sensed the disturbance caused by Lawrence III.
A Venomoth appeared in a fantasy in The Rivalry Revival.
In Illusion Confusion!, a group of Haunter and Gengar created the illusion of a Venomoth.
In The Bug Stops Here, a Venomoth was prompted to use Stun Spore after being scared by Jessie, who was dressed as a Venomoth in order to attract Bug-type Pokémon.
A Venomoth appeared in Celebi: The Voice of the Forest.
Multiple Venomoth appeared in the opening sequence of Destiny Deoxys.
A Venomoth appeared in the opening sequence of Lucario and the Mystery of Mew.
A Coordinator's Venomoth appeared in What I Did for Love!.
A Venomoth appeared in The Ole' Berate and Switch!, under the ownership of a Team Rocket Grunt.
In Staging a Heroes' Welcome!, a Coordinator's Venomoth competed in the Performance Stage of the Wallace Cup.
A Venomoth appeared in a flashback in A Trainer and Child Reunion!.
A Venomoth made a cameo appearance in Arceus and the Jewel of Life.
In I Choose You!, a Venomoth fell under the control of Marshadow.
||Venomoth, an evolved form of Venonat. Tiny scales on its wings disperse various spores when they are flapped.
In The Show, a Venomoth was used to provide special effects for the Kimono Girls' performance.
A Venomoth appeared in The Discovery, under the ownership of a Bug Catcher. It was used to challenge Green to a battle and lost almost immediately.