Alomomola debuted in In The Shadow of Zekrom!. It was the first Pokémon in the Unova region that Ash saw.
In The Name's N!, N asked two Alomomola to use Refresh on Pikachu, who was suffering from Paralysis.
In Big Sky, Small Fry!, an Ally Alomomola tried to assist a Totem Wishwashi during Lana's trial.
In A Fishing Connoisseur in a Fishy Competition!, an Alomomola was hooked by a competitor in Team Rocket's fake fishing contest.
Multiple Alomomola appeared in White—Victini and Zekrom and Black—Victini and Reshiram.
An Alomomola appeared in a flashback in The Four Seasons of Sawsbuck!.
Multiple Alomomola appeared in Stopping the Rage of Legends! Part 1 and Part 2.
An Alomomola appeared in All for the Love of Meloetta!.
Multiple Alomomola appeared in Piplup, Pansage, and a Meeting of the Times!.
In Expedition to Onix Island!, an Alomomola was living at a deserted island.
An Alomomola appeared in a fantasy in New Places... Familiar Faces!.
In Going for the Gold!, multiple Alomomola were living in the Ambrette Aquarium.
Multiple Alomomola appeared in An Undersea Place to Call Home!.
Two Alomomola appeared in Day Three Blockbusters!. One appeared in a flashback that showed Ash catching it for a fishing competition, while the other was under the ownership of a Trainer who participated in the Pokémon Summer Camp.
An Alomomola appeared in Alola to New Adventure!.
Two Alomomola appeared in The Guardian's Challenge!.
Two Alomomola appeared in Yo, Ho, Ho! Go, Popplio!, with one being wild and the other appearing in a fantasy. Lana hooked the wild one whilst fishing and gave it some food.
Multiple Alomomola appeared in The Sun, the Scare, the Secret Lair!.
Multiple Alomomola appeared in Balloons, Brionne, and Belligerence!.
Three Alomomola appeared in Now You See Them, Now You Don't!.
An Alomomola appeared in Pikachu's Exciting Adventure!.
An Alomomola appeared in Looking Out for Number Two!.
Alomomola appears to be a combination of an ocean sunfish and a heart representing health. Due to its hand-like fins and heart shaped body, it may have been inspired by the Claddagh ring. Its ability to heal other Pokémon may be inspired by the doctor fish. The fact that it wraps itself in a special membrane might be a reference to a parrotfish, or the nourishing secretions of the discus fish. Alomomola being found in locations with the Jellicent line, reflects the ocean sunfish's diet of jellyfish.
Alomomola may be a combination of Mola mola (scientific name for the ocean sunfish) and mom. It may also involve aloha (Hawaiian for love).
Mamanbou may be a combination of mama and 翻車魚 manbō (ocean sunfish).