The Dragon's Den is inaccessible before defeating Clair in the Blackthorn Gym, as it is blocked off by a man in front of the cave. After defeating Clair, it must be traversed to obtain the Rising Badge.
Silver can be found here contemplating his training on Tuesdays and Thursdays. Clair will visit to reward the player with the Rising Badge she refused to award in the Blackthorn Gym, as well as TM24 (DragonBreath)GSC or TM59 (Dragon Pulse)HGSS. This requires completing the quiz described above. In Pokémon Gold and Silver, where the Dragon Shrine is closed and everything related to it is unavailable, Clair will instead give the Rising Badge to the player after they collect the Dragon Fang.
In Pokémon HeartGold and SoulSilver, after the player battles Silver at Mt. Moon, they can participate in a Multi Battle with him against Lance and Clair here. Also, in these games, if the player receives the Rising Badge from Clair and then leaves the Dragon's Den with Dig, Teleport, or an Escape Rope, then they must return to her Gym in order to collect the TM.
It is a prize for correctly answering the questions given by the Master in the Dragon Shrine. If any wrong answers are given, the player will still receive a Dratini but it will have Leer instead of ExtremeSpeed.
After completing the quiz, the player will then need to receive TM24 (DragonBreath)C or TM59 (Dragon Pulse)HGSS from Clair. After this, returning to the Master will result in him giving the Dratini to the player.
The Dragon's Den appeared in Fangs For Nothin', where it was reduced to a series of tunnels leading to the Dragon Holy Land. The Dragon Holy Land takes over for the Dragon's Den's other roles in the anime, including the location of the Dragon Shrine and the Dragon Fang.
The Dragon's Den appeared in Debonaire Dragonair. Clair encountered and battled Suicune here, but failed to defeat and catch it. According to Clair, only the Pokémon living on the site with her family are allowed here.
Dragon's Den is the only location where the player obtains a Gym Badge that is not a Gym.
In Pokémon Crystal, if the player whites out due to poison damage while still inside the Dragon Shrine after receiving the Rising Badge, they can return to the Blackthorn Gym to receive the reward TM from Clair. However, if the player then returns to Dragon's Den and stands on the tile directly in front of the Dragon Shrine's door, Clair will appear again and give the player another TM24.