Route 44 is straightforward and easy to navigate. It is forked around a pair of calm ponds. Trainers gather on either side of the ponds, and provide a challenge before the chilling Ice Path. Battling wild Pokémon is entirely optional, as the only patch of straight grass is surrounded by a pair of calm ponds. The Pokémon found here, however, are rarely found elsewhere in the Johto region. Remoraid, for example, can only be found on this route. Some Pokémon from faraway regions can be lured here if the right radio station is playing.
Trainers with a telephone symbol by their names will give their Pokégear number to the player, and may call or be called for a rematch with higher-level Pokémon.
A graphical glitch occurs on this route in Pokémon HeartGold and SoulSilver. Three tiles at the top of the grassy patch appear to be empty at first glance, but when the player (or his or her partner Pokémon) walks over the tiles, tall grass will appear underfoot. At most two of the three tiles will be grassy, allowing for comparisons to be made between the tiles.