The route is essentially straightforward after exiting Ilex Forest. There is a path where no long grass grows, however, it is filled with many Trainers. This road can be difficult if a Trainer doesn't go back to Azalea Town to heal their Pokémon after facing his/her rival in the forest.
The Day Care, run by an old couple, is one of the most prominent things located here. Found merely steps away from the famous Goldenrod City, this center allows for compatible male and female Pokémon to breed and produce an Egg. It also allows Trainers to leave up to two of their Pokémon to level up, costing like other Pokémon Day Cares, 100 plus an additional 100 per level up for each Pokémon. In the Generation II games, the player can enter the Day Care's backyard to interact with their Pokémon and surf or fish in the pond, but this is not possible in Pokémon HeartGold and SoulSilver due to the Pokémon now being off-limits to the player in an area inside the Day Care itself.
After getting Surf, a secret area of the route is accessible. It has three Ace Trainer sisters: Irene, Jenn and Kate, who the player will battle in that order in Generation II. In HeartGold and SoulSilver Versions, Irene and Jenn will instead battle a Double Battle with the player.
Trainers with a telephone symbol by their names will give their Pokégear number to the player, and may call or be called for a rematch with higher-level Pokémon.
Berry trees grow new Berries every day. Make a note of which trees bear which berries.
North to Goldenrod City The Radio Tower at Goldenrod is giving away Radio Cards. Answer their questions and receive a Radio Card!
In Pokémon HeartGold and SoulSilver, there is a glitch with Ace Trainer Kate. She will only battle the player if they walk straight down the path. If the player walks to either side of her, she will apologize as she would after the player has defeated her. If the player walks down the path towards her after talking to her on the side she will somehow see them while facing the wrong way and then battle.
In the Japanese versions, the three Ace Trainer sisters all have names which start with "Mari".
The Day Care man has an unused piece of dialogue in the Generation II games, "Not yet...". This would likely be used during the breeding process to notify the player that the game needs more time to generate the Egg.