The lab researches various aspects of Pokémon, such as their ecosystems and battling. For the latter purpose, the lab houses a Battle Simulator, where the player can experience several tutorial battles against Sim Trainers. The most notable feature of the lab, however, is the Purify Chamber, which Professor Krane created in case if Shadow Pokémon were ever to resurface. This device, once completed, allows the player to purify Shadow Pokémon much more effectively than in Pokémon Colosseum. Krane also developed the Aura Reader and a new Snag Machine as tools to recognize and snag Shadow Pokémon.
Trainers with a Poké Ball by their names may be challenged for a rematch after defeating certain bosses. In a rematch they may have higher-level Pokémon, and any Shadow Pokémon previously caught will be replaced.
A Kecleon is hiding on the table close to where Adon is hiding.
Early in the game, the player can talk to the receptionist in the east wing about previous Shadow Pokémon incidents; there is a typographical error in one of her explanations, with two dots ("..") appearing where an ellipsis ("...") would be expected.