Original Series and Legendary Collection Series
This card was released as a Trainer card in the Base Set with artwork by Keiji Kinebuchi, first released in the Japanese Expansion Pack. Before the TCG was officially released in North America, prototype Pokémon Leagues were given the Trainer Deck A, which included this card. The cards in this deck all have a red border and "Trainer Deck A" printed on the back. In Japan, it was reprinted in the Nivi City, Hanada City and Guren Town Gym Decks. It was also included in the Red and Green Decks of the Japanese Quick Starter Gift Set as well as the Bulbasaur and Squirtle Decks of the Japanese Intro Pack. Both of these prints featured reworded effect text to the original. Outside Japan, it was reprinted in Base Set 2 and the Legendary Collection retaining its original effect text. Potion was also featured in the Pokémon Trading Card Game and Pokémon Card GB2: Here Comes Team GR! for Game Boy Color.
Although no reprints were made during the Neo Series, the Japanese Neo Era saw the release of the Intro Pack Neo, which included reprints of Potion in its Chikorita and Totodile Half Decks. This print featured more amended effect text wording.
In Japan, this card was reprinted in the Tyranitar Half Deck followed by a release in the Pokémon VS expansion. This print was also included in a slightly altered version of the Tyranitar Half Deck, which was distributed to players at the 2001 Tropical Mega Battle and was available in several languages. The Japanese and German prints featured slightly reworded effect text.
It was reprinted in the Expedition Base Set with new artwork by the same artist, first released in the Japanese Pokémon-e Starter Deck. It was reprinted in the Japanese Theater Limited VS Pack.
Potion was reprinted again in the EX Ruby & Sapphire expansion, originating from the Japanese Treecko, Torchic and Mudkip Constructed Starter Decks. In Japan, it was reprinted in the Flygon Constructed Starter Deck, Salamence Constructed Starter Deck, Metagross Constructed Starter Deck, Movie Commemoration VS Pack, Magma Deck Kit, Aqua Deck Kit, Gift Box, and the Metagross Constructed Starter Deck. It was also reprinted in the EX Trainer Kit. It was reprinted again in the EX FireRed & LeafGreen expansion, first released in the Venusaur, Charizard, and Blastoise Random Constructed Starter Decks. In Japan, it was reprinted again in the Rayquaza Constructed Starter Deck, Deoxys Constructed Starter Deck, Movie Commemoration VS Pack: Sky-Splitting Deoxys, Black Deck Kit, Silver Deck Kit, as well as the Grass, Lightning, and Fighting Quick Construction Packs. It was reprinted yet again in the EX Trainer Kit 2.
A new print with artwork by Shin-ichi Yoshikawa and updated effect text was included in the EX Unseen Forces expansion, first released in the Japanese Meganium, Typhlosion and Feraligatr Constructed Starter Decks. In Japan, it was reprinted in the Mirage's Mew Constructed Starter Deck, Master Kit, and the Movie Commemoration VS Pack: Aura's Lucario. It was reprinted in the EX Delta Species expansion, first released in the Japanese Holon Research Tower Water Quarter Deck. In Japan, it was reprinted again in the Gift Box Mew • Lucario, Ocean's Kyogre ex and Earth's Groudon ex Constructed Starter Decks (which led to a reprint in the EX Crystal Guardians expansion), Imprison! Gardevoir ex Constructed Standard Deck, Movie Commemoration VS Pack: Sea's Manaphy, and the Infernape Half Deck of the Entry Pack.
Diamond & Pearl Series
Potion was reprinted during the Diamond & Pearl Series in the Diamond & Pearl expansion, first released in the Japanese Space-Time Creation expansion. It was reprinted again in the Japanese Rampardos the Attacker Deck and the Diamond & Pearl Trainer Kit. It was reprinted once again in the Secret Wonders expansion, first released in the Japanese Palkia LV.X Constructed Standard Deck. It was also reprinted in the Stormfront expansion and the Japanese Magmortar vs Electivire Deck Kit, Entry Pack '08.
No reprints were made during the Platinum Series; however, the Japanese DPt Era included several products carrying Potion reprints: the Gift Box DPt, the Arceus LV.X Deck: Grass & Fire, and the Arceus LV.X Deck: Lightning & Psychic.
Black & White Series
Potion was reclassified as an Item card during the Black & White Series in the Black & White expansion with artwork by Ayaka Yoshida, first released in the Japanese Beginning Set. It was also included in the Black & White Trainer Kit. It was reprinted in the Boundaries Crossed expansion, first released in the Japanese National Beginning Set. It was reprinted again in the Japanese Everyone's Exciting Battle collection.
Potion was reprinted again during the XY Series in the Kalos Starter Set with new artwork by 5ban Graphics, first released in the Japanese XY Beginning Set. It was reprinted in the Japanese Xerneas Half Deck. It was reprinted in both Half Decks of several Deck Kits, namely the XY Trainer Kit, XY Trainer Kit: Bisharp & Wigglytuff, XY Trainer Kit: Latias & Latios, the Japanese Emboar-EX vs Togekiss-EX Deck Kit (which led to a reprint in the BREAKpoint expansion), and the XY Trainer Kit: Pikachu Libre & Suicune. In Japan, it was reprinted again in the BREAK Starter Pack. An unnumbered XY-P Promotional print was 1 of 9 cards available in special packs sent to Event Organizers in Japan starting July 2016, which were then distributed to participants of subsequent official events held by them. This print features the Event Organizer logo in the bottom right corner of the illustration. It was reprinted as a retro card in the Evolutions expansion, first released in the Japanese Expansion Pack 20th Anniversary subset, featuring the same artwork as the original print and an updated card template reminiscent of the Original Series layout.
Sun & Moon Series
During the Sun & Moon Series, Potion was reprinted as part of the Sun & Moon expansion with new artwork by Toyste Beach, first released in the Japanese Sun & Moon Starter Set. This print was reprinted in the Alolan Raichu Half Deck of the Sun & Moon Trainer Kit: Lycanroc & Alolan Raichu, released April 21, 2017. In Japan, it was later reprinted as part of the Ash Half Deck in the Ash vs Team Rocket Deck Kit, in the Ultra Sun expansion, in four of the nine GX Starter Decks, and in the Sun & Moon Family Pokémon Card Game set. The Sun & Moon Trainer Kit: Alolan Sandslash & Alolan Ninetales included a variant of the Sun & Moon print. It has a 15 in a blue circle at the bottom right of the card, so the deck can be ordered for a practice duel. The Sun & Moon print of Potion had five variants within the Battle Academy deck kit. The cards within the three decks (Charizard, Pikachu, and Mewtwo) had a silhouette of the Pokémon in the bottom right of the card, with the Charizard and Pikachu Deck cards also having numbers so they could be ordered for a practice duel. One copy was part of the Mewtwo Deck, while the other two decks had two copies each. The numbers on the Charizard Deck copies are 14 and 37; the numbers on the Pikachu Deck copies are 20 and 40.
Sword & Shield Series
Potion was reprinted during the Sword & Shield Series with new artwork by Ryo Ueda, appearing in the Sword & Shield expansion, first released in the Japanese V Starter Set Grass. In Japan, it was reprinted as a S-P Promotional card with the collection number 017/S-P and was available in the Grookey, Scorbunny & Sobble Card Box, released on December 6, 2019. Another S-P Promotional print, this time with the collection number 051/S-P, was one of nine possible cards included in special packs sent to Event Organizers in April 2020 for distribution in official events hosted by them. This print features the Event Organizer logo in the bottom right corner of the illustration. The Sword & Shield print was reprinted again in Japan in two of the nine V Starter Decks, in the Venusaur VMAX Starter Set, in the Sword & Shield Family Pokémon Card Game set, in the Start Deck 100 (available in both Non Holofoil and Mirror Holofoil versions), and as a Mirror Holofoil in the Start Deck 100 CoroCoro Comic Version. Outside Asia, it was reprinted in the special Champion's Path and Crown Zenith expansions.
Scarlet & Violet Series
During the Scarlet & Violet Series, this card was reprinted in the ex Starter Set Sprigatito & Lucario ex with different artwork by Ayaka Yoshida.