Permanently missable items
This page does not include items that are missed by choosing another item (such as mutually exclusive Fossils), items missable due to exploiting glitches, nor event items. Furthermore, items that can no longer be obtained after the internal battery of Pokémon Ruby, Sapphire, or Emerald runs dry are also excluded.
In the core series
Only in Generation I games, five Poké Balls can be obtained from Professor Oak after defeating the rival on Route 22 if the player has bought no Poké Balls and has added no caught data to the Pokédex aside from starter Pokémon.
|Poké Ball ×5||Obtained from Professor Oak after defeating the rival on Route 22 if the player has bought no Poké Balls and has added no caught data to the Pokédex aside from starter Pokémon||R B Y|
This item can only be obtained if Surf is used while the S.S. Anne is still in Vermilion Harbor. Once the S.S. Anne leaves the player cannot access the area in which Surf must be used again. In Pokémon: Let's Go, Pikachu! and Let's Go, Eevee!, the port is on the same map as Vermilion City and can be accessed at any time once their Partner learns Sea Skim.
|Lava Cookie||Far southeast of the truck, in the southeast corner, only accessible while the S.S. Anne is moored in Vermilion Harbor (requires Surf) (hidden)||FR LG|
In the Generation I games, exploiting a glitch can allow the player to board the S.S. Anne after it has left. In Pokémon: Let's Go, Pikachu! and Let's Go, Eevee!, the player can receive extra Poké Balls for defeating the Trainers on the ship, but if the player doesn't battle a Trainer before learning the Secret Technique from the captain, that Trainer will act as if already defeated and cannot be battled.
|Hyper Potion||B1F, on the trash can in the lower right corner (hidden)||FR LG|
|Max Potion||B1F, in the first room from the right||R B Y|
|Super Potion||B1F, in the first room from the right||FR LG|
|Ether||B1F, in the third room from the right||R B Y FR LG|
|Full Heal||B1F, in the third room from the right (item closer to the door)||P E|
|Elixir||B1F, in the third room from the right (item further from the door)||P E|
|TM44 (Rest)||B1F, in the fourth room from the right||R B Y FR LG|
|Super Potion||B1F, in the fourth room from the right||P E|
|Hyper Potion||B1F, in the fifth room from the right, in the lower left cornerRG or on the bed's pillowRBY (hidden)||R B Y|
|TM08 (Body Slam)||1F, in the second room from the left||R B Y|
|TM31 (Brick Break)||1F, in the second room from the left||FR LG|
|Paralyze Heal||1F, in the second room from the left||P E|
|Great Ball||Kitchen, in the lower left corner||FR LG|
|Super Repel||Kitchen, in the lower left corner||P E|
|Great Ball||Kitchen, on the lowest trash can (hidden)||R B Y|
|Chesto Berry||Kitchen, on the lowest trash can (hidden)||FR LG|
|Tiny Mushroom||Kitchen, on the lowest trash can (hidden)||P E|
|Cheri Berry||Kitchen, on the middle trash can (hidden)||FR LG|
|Pecha Berry||Kitchen, on the on the uppermost trash can (hidden)||FR LG|
|Max Ether||2F, in the second room from the left||R B Y|
|Stardust||2F, in the second room from the left||FR LG|
|Revive||2F, in the second room from the left||P E|
|Rare Candy||2F, in the fourth room from the left||R B Y|
|X Attack||2F, in the fourth room from the left||FR LG|
|Nugget||2F, in the fourth room from the left||P E|
|Pinap Berry ×3||Deck, under the lower left table (hidden)||P E|
|Poké Ball ×36||Reward for defeating Trainers on the ship||P E|
In Pokémon: Let's Go, Pikachu! and Let's Go, Eevee!, if the player hasn't defeated Juggler Dalton before defeating Giovanni at the top floor of the Silph Co., he will disappear from the building, along with the rest of the Trainers associated with Team Rocket, and the three Poké Balls he hands out upon being beaten become unobtainable.
|Poké Ball ×3||Reward for defeating Juggler Dalton||P E|
In the Generation II games, the Slowpoke Tail can be bought for 9800 in Just a Souvenir Shop prior to speaking to Lance at the Lake of Rage. Once Lance opens the secret entrance to the Team Rocket HQ, the salesman no longer sells anything, and once the player has cleared the HQ, the Slowpoke Tail is not a part of the new merchant's selection of buyable items. The tail isn't available for sale at the shop at any point during Pokémon HeartGold and SoulSilver, even though it exists in the game's coding.
|Just a Souvenir Shop|
After clearing a room, the Trick Master rebuilds the puzzle room into the next one. After clearing the final room, the Trick Master leaves and the player cannot access the puzzle room anymore.
|Orange Mail||Puzzle 1, in middle area of the maze (requires Cut)||R S|
|Orange Mail||Puzzle 1, in the north part of the maze, west of the exit (requires Cut)||E|
|Lava Cookie ×2||OR AS|
|Wave Mail||Puzzle 2, near entrance||R S E|
|Harbor Mail||Puzzle 2, far northeast corner of room||R S|
|Harbor Mail||Puzzle 2, middle area of room, past the second hole||E|
|Rage Candy Bar ×2||
|Wood Mail||Puzzle 3, near Picnicker Martha||R S|
|Wood Mail||Puzzle 3, far northwest corner, past sliding door||E|
|Shadow Mail||Puzzle 3, near Hiker Alan||R S|
|Shadow Mail||Puzzle 3, behind Picnicker Martha||E|
|Lumiose Galette ×2||
|Mech Mail||Puzzle 4, near Black Belt Yuji||R S|
|Mech Mail||Puzzle 4, near Battle Girl Cora||E|
|Casteliacone ×2||OR AS|
|Old Gateau ×2||
|Glitter Mail||Puzzle 6, near exit of room||R S|
|Glitter Mail||Puzzle 6, in the southeast part of the maze||E|
|Shalour Sable ×2||
|Tropic Mail||Puzzle 7, to the right of Hex Maniac Patricia||R S|
|Tropic Mail||Puzzle 7, in center of room, via transport tile||E|
|Bead Mail||Puzzle 8, between the upper and lower area||R S|
|Bead Mail||Puzzle 8, northwest area of room||E|
|Nugget||Prize room, under the Trick Master's cushion after completing Puzzle 8 (hidden)||R S E|
|Big Nugget||Prize room, under the Trick Master's cushion after completing Puzzle 6 (hidden)||OR AS|
Magma and Aqua Hideouts
|Master Ball||Middle room on 2nd floor, the top-left item a cluster of two real and two fake items, just after a maze of teleports||R S|
|Nugget||The bottom-left item in the same cluster as the Master Ball||R S|
|Max Elixir||Near generator-like thing on 2nd floor, accessible with right teleport near stairs||R S|
|Nest Ball||West-middle room on 3rd floor||R S|
|Ultra Ball||Top floor, from Zinnia if the player has no Poké Balls in their Bag (repeatable)||OR AS|
Dry Lake Valor
In Pokémon Diamond, Pearl, and Platinum, Lake Valor is initially drained by a Galactic Bomb, allowing the player to walk across the lakebed. After Dialga, Palkia, or Giratina has been caught or defeated, the lake is refilled and the player can no longer access the HP Up on the lakebed.
|HP Up||In the northwest while the lake is dry (hidden)||D P Pt|
|Max Potion||In the right room on the second floor||B W|
|Max Revive||In the center room on the third floor||B W|
|Ultra Ball||Gift from a Team Plasma Grunt in the left room on the third floor (repeatable if the player has no Poké Balls in their Bag)||B W|
|Rare Candy||Inside N's room||B W|
|Full Restore||In the center room on the fourth floor||B W|
In Pokémon Sun and Moon, when battling SolgaleoS/LunalaM at the Altar of the SunneS/Altar of the MooneM, if the player has no Poké Balls (of any kind) in their Bag after defeating or running from Solgaleo/Lunala, Lillie will give the player 10 standard Poké Balls.
|Poké Ball ×10||From Lillie if the player has no Poké Balls in their Bag after defeating or running from SolgaleoS/LunalaM (repeatable)||S M|
In Pokémon Sword and Shield, the player can accept a request from a boy near the northwest Pokémon Center to find a lost Minccino. If the player heads to Motostoke Stadium and checks around the fountain to the right of the building, they will find a man who will give them a Fresh Water. Once the Minccino is found and returned, the player is unable to obtain the Fresh Water.
|Fresh Water||Obtainable from a man in the Motostoke Stadium fountain to the right of the entrance after accepting to look for the lost Minccino||Sw Sh|
In the side series
Pokémon XD: Gale of Darkness
In Pokémon XD: Gale of Darkness, Eagun's two Pikachu are holding a Light Ball each during the post-game battle against him at the Pokémon HQ Lab. These items can be stolen with Thief or Covet during the battle, but if they're not, they become unobtainable, as Eagun cannot be rematched.
|Light Ball ×2||Held by Eagun's two Pikachu during the post-game battle at the Pokémon HQ Lab||XD|
In the spin-off games
Trading Card Game series
In Pokémon Trading Card Game, a Lad in the west room of the Fire Club asks the player to give him all his unused Energy cards. If the player complies, he receives a Slowpoke card. If the player refuses, the Lad goes away without giving him the Slowpoke card.
In Pokémon Card GB2: Here Comes Team GR!, it is possible to delete mail from the Minicom without reading it or getting any attached booster packs. The mail and attached booster packs cannot be recovered if deleted.
|This item article is part of Project ItemDex, a Bulbapedia project that aims to write comprehensive articles on all items.|