In order to defeat them, the player must infiltrate their Sky Fortress, where the Societea is headquartered. After defeating the Societea executives, who use Crobat, Ditto and Regigigas, the player must do battle with their leader's Mewtwo. However, when Mewtwo is captured, Purple Eyes suddenly appears and betrays the Societea, seizing control of Mewtwo using a special suit of armor. The player must capture Mewtwo again to defeat Purple Eyes and put an end to his schemes.
It is stated that originally, the Pinchers were just loosely-associated mercenary groups around the world, and that it was the Societea that gathered these groups into a formal team and installed Purple Eyes as its leader. Throughout the game, the Pokémon Pinchers Grunts appear in Quests, sometimes even as the client.