In the main series
Chansey first appeared in Pokémon Emergency! where two of them wheeled Ash's Pikachu into the emergency room after he was injured badly from a flock of Spearow Ash was protecting Pikachu from.
Another Chansey appeared in Electric Shock Showdown, where she was seen wheeling in a Pidgey after it fought a losing Gym battle against Lt. Surge. This caused Ash to worry about his upcoming Gym battle with Lt. Surge and Pikachu to become frightened about fighting the Gym Leader.
In Showdown at Dark City, a Nurse Joy sent out Chansey while revealing that she was undercover as an inspector for the Pokémon Inspection Agency.
While Ash and his friends were in Dr. Proctor's hospital in A Chansey Operation, Chansey wheeled in some injured Pokémon to Dr. Proctor's hospital as an extra room was needed since the Pokémon Center was full. Chansey then helped heal Team Rocket's Pokémon and Meowth. When Team Rocket battled Ash and his friends, Chansey prevented them from doing so and as Chansey cared for Arbok and Weezing earlier while they were injured, Arbok and Weezing refused to fight Chansey. After all the Pokémon were healed, Dr. Proctor and Chansey waved goodbye to Ash and his friends.
In The Joy of Pokémon, a Chansey traveled on a kayak with her Nurse Joy from island to island to treat injured Pokémon.
In Pokémon Food Fight!, Chansey was seen with Nurse Joy while announcing the shipment of food delay to Butwal Island.
Matsuko, Takeko, and Umeko
Jessie of Team Rocket was revealed to have once befriended a Chansey, which later met again, having evolved into Blissey. This Blissey appeared in Ignorance is Blissey.
In Hour of the Houndour, a Chansey along with Nurse Joy bought groceries earlier and noticed an ice cream truck. They went to buy ice cream and then noticed their ham bag is empty. Later, Chansey took care of a wounded Houndour.
The Nurse Joy of Lake Lucid has three Chansey that are nicknamed (Japanese: マツコ Matsuko), (Japanese: タケコ Takeko) and (Japanese: ウメコ Umeko), as seen in The Joy of Water Pokémon.
In A Tail with a Twist, after Treecko was beaten by a wild Seviper, Chansey and Nurse Joy took care of Treecko. When Treecko disappeared from the Pokémon Center, Chansey ran off to warn Nurse Joy about the situation.
In A Double Dilemma, Rose delivered some groceries to the Pokémon Center and gave them to Chansey. During the delivery, she and Nurse Joy recognized that May and Max returned to North Petalburg.
Kanto Battle Frontier
In Overjoyed, in an attempt for Ash to warm up for his rematch against Brandon, Nurse Joy decided to battle Ash with her Chansey in May's place while Ash sent out his Ash's Corphish. As none of Corphish's attacks did any damage to Chansey, Chansey went on to defeat Corphish with Solar Beam. After the battle, Chansey and Nurse Joy took Corphish to heal up on a stretcher. When Team Rocket watched the battle, they were interested in Chansey because of the fact that she was strong. They did so by having Wobbuffet disguise himself as a Blissey. Team Rocket was able to grab Chansey but Chansey easily defeated Team Rocket. Afterwards, Chansey watched Ash's rematch against Brandon.
The Chansey in Fennel Valley reappeared in Pinch Healing! where she witnessed Nurse Joy unconscious from a flu. She stayed by Nurse Joy's side as she lied down in bed until she felt better.
Nurse Joy and her Chansey
In One Big Happiny Family!, when Ash and his friends went to a Pokémon Center while on their way to Hearthome City, a Chansey appeared and showed them where Nurse Joy was. Chansey then helped Nurse Joy with the hatching of Brock's Happiny Egg in which they were successful. Chansey then partook in the battle against Team Rocket.
One of them was used in battle under the ownership of a PIA Nurse Joy in DPS02. She battled Brock's Sudowoodo at the Pewter Gym. Sudowoodo fell for Chansey's Attract and was defeated with an Egg Bomb; not laying a single hit.
Following Ash's arrival in Unova, Audino were featured instead of Chansey, as Chansey was not native to Unova.
After a long absence, another one appeared in BWS01.
Personality and characteristics
Chansey is similar to her Trainer, Nurse Joy, as both are caring and nice to Trainers and Pokémon. Chansey usually assists Nurse Joy when a Trainer comes in and escorts the Pokémon on a stretcher. Despite being caring, Chansey is able to hold her own in battle, first evident in Overjoyed! where the one owned by the Nurse Joy was not only a good nurse, but a good battler as well. Chansey was able to defeat Ash's Corphish in an informal battle the two had as a result. During that battle, it was shown that Chansey, along with Nurse Joy, were more fierce towards opponents. After the battle, they revert back to their normal selves.
| Using Solar Beam
| Using Double Slap
| A † shows that the move was used recently, unless all moves fit this case or there are fewer than five known moves.
Chansey is Nurse Joy's only known Pokémon. She helps her with nursing Pokémon at the Pokémon Center. Three different Chansey belonging to three different Nurse Joy appeared in I Choose You!.
One appeared working alongside Nurse Joy in a Pokémon Center in a forest, where she helped taking care of an injured Vaporeon. Another Chansey belonging to a second Nurse Joy worked alongside her in a Pokémon Center in an unnamed town. She helped take care of Ash's Charmeleon after it got badly injured in a battle with Cross. A third Chansey worked alongside its Nurse Joy in a Pokémon Center near a lake, close to the Raizen Mountains. It helped heal Ash's Pikachu after he had battled with Ho-Oh.