It was first used in Heart of Fire! Heart of Stone! to help him calm down an angry Kangaskhan mother that was protecting her injured baby, which it did by using Sweet Scent. Comfey then helped Brock treat the injured baby Kangaskhan, handing him medicine and bandages.
Personality and characteristics
As with all of its species, Comfey has been shown to be kind and caring, as well as able to calm down angry Pokémon. Comfey has a good amount of skill dealing with injured Pokémon, helping both Brock and Nurse Joy treat injured and upset Pokémon.