On the way to Celestic Town, Ash and his friends are camped at a mountain cabin. While Dawn trains and Ash snoozes, Brock goes down the mountain to visit a pharmacy. That leaves Ash and Dawn in charge of the Pokémon, and their first task is to give the Pokémon a shower. Ash accidentally blasts Pachirisu with cold water, but everything seems to go smoothly. After that, it's lunchtime and a siesta! But naptime is cut short when Pachirisu comes down with a bad fever and there's no Pokémon Center in the area.
While Staravia goes out to find Brock, Ash has Buneary use Ice Beam to make an ice pack for Pachirisu's fever. The little Pokémon is still unwell, and Dawn and Ash argue over whose fault it was before they realize they need to find the berries that Brock uses for sick Pokémon. Meanwhile, Team Rocket sees a Zapdos fly by and try to hit it with a cannon full of sticky goo, but they hit Staravia instead. It manages to evade them, but now it can't fly. When Staravia fails to return, Ash sends Gliscor out to get Brock instead.
Alerted by Gliscor, Brock runs back to the cabin and realizes that Pachirisu may have a build-up of excess electricity. Once he drains the extra charge and treats Pachirisu with medicine and Oran Berries, it's on its way to a speedy recovery—just in time to be stolen by Team Rocket, who spotted the cabin! But Staravia found some friendly Wooper to clean the gunk off its wing, and it returns in time to free Pachirisu from Team Rocket's net. Then Buneary and a healthy Pachirisu team up to blast Team Rocket back where they came from. It looks like a happy ending all around, except that they forgot about one Pokémon: poor Gliscor, still struggling up the long road back to the cabin!
While Dawn practices Contest moves, Ash begins thinking of a counter strategy to overcome Fantina's Drifblim and its Hypnosis. He ends up falling asleep trying to think, so Pikachu wakes him up, slightly annoyed. Brock emerges from the cabin and prepares to head off to a nearby pharmacy to stock up on medicinal supplies. He leaves Ash and Dawn in charge of chores and all the Pokémon, before heading off.
Ash reads the list of chores, and first up are showers for the Pokémon. When it's Pachirisu's turn, Ash accidentally sprays it with cool water. Dawn scolds him, and quickly turns on the warm water. With everyone showered, Dawn and Pikachu whip up a batch of pancakes to feed them all. Things become chaotic when Pachirisu comes down with a fever, and learn that there isn’t a Pokémon Center nearby. Ash suggests they get Brock back, and he sends Staravia off, much to Gliscor's disappointment. Dawn is still worrying, and Ash takes Buneary and Happiny to make ice to bring Pachirisu's fever down. Dawn puts the ice on Pachirisu's head, then yells at Ash for spraying it with cold water earlier. Ash counters by saying it probably has an upset stomach because of those pancakes she fed it. The two argue until Dawn hears her sick Pokémon's voice, and they agree it's no time to fight. In the meantime, Ash and Dawn venture outside to find some Oran Berries to aid Pachirisu's recovery. However they fail to find any berries in their search.
Flying in their Meowth balloon, Team Rocket spots a Zapdos flying past, and they want it. James fires a Bazooka Gun, but Zapdos flies up. The wad instead hits Ash’s Staravia, and Jessie tells them they can change their sights to that one instead. Team Rocket scour the forest carefully for Staravia, who has since landed and trying to clean its stuck wing of the glue.
Returning to the cabin, Ash grows concerned about Staravia as it still hasn't returned, so Gliscor offers to go get Brock instead. Ash sends it off, shouting for it to go to the right and calm down. Brock has since finished his shopping and on his return to the cabin he spots Gliscor flying directly for him. He tries to run out of the way, but Gliscor lands on him. Brock realizes something is amiss from Gliscor's frantic gestures and begins to run back to the cabin. He stops after realizing Gliscor needs wind to fly, otherwise it is forced to bounce along the ground causing it to often trip and fall. He offers to carry Gliscor, though Brock is forced to leave it behind and rush on ahead.
Dawn and Ash know they need to get Pachirisu to eat, and Dawn recalls when she was sick, her mom fed her mashed fruit. Ash says they still have the fruit Pikachu found, and try feeding it but Pachirisu refuses. Brock runs in and checks over Pachirisu. Telling Ash and Dawn they need to establish what's wrong before trying to treat it, he diagnoses the problem as a fever caused by a build-up of electricity in Pachirisu's body, which Ash recalls happened to Pikachu once. He gets the electricity out with a device and gives Pachirisu some medicine to help it regulate its voltage back to normal. Brock tells Ash and Dawn that in a situation like this they need to remain calm instead of panicking like they did. Ash and Dawn both feel terrible, and Dawn begins to cry at the thought of how badly she acted when Pachirisu needed help, and Ash tries to comfort her. They tell Brock about the mashed fruit, but he says that doesn't come until later. Brock teaches Ash and Dawn that when they were looking for Oran Berries they'd looked in the wrong place, as the soil was too dry. He then leads them to a damper area, where some bushes of Oran Berries growing. They rush back to cabin where they feed Pachirisu the Oran Berries, which it happily accepts. At the same time, Staravia gets help from some Wooper to get the gunk off its wings.
Pachirisu shows everyone it's better by running around, only to be grabbed by a net. Everyone runs outside, demanding an explanation. They look up to see Team Rocket, who recite their motto. They say they wanted Pikachu, but they'll take Pachirisu instead. This infuriates Dawn. Staravia finally returns. James fires off another Bazooka Wad at it, though Staravia flaps its wings to send it back at the Rocket trio. Staravia follows up with Aerial Ace to cut the net, releasing Pachirisu. Buneary steps up and freezes Team Rocket with Ice Beam before pounding them with Dizzy Punch. Pachirisu is raring to go, so Dawn has it send Team Rocket blasting off with Discharge.
Brock warns Ash and Dawn that this situation could happen again, and suggests he teaches them first aid in case something happens and they can't find a Pokémon Center. They agree knowing that when things get tough, a Pokémon relies on its Trainer the most. Brock offers to make food, and Pachirisu confirms it's better by being hungry. With Ash and Dawn having learned somes valuable lessons, the group returns to the cabin to enjoy the rest of the evening. Ash suddenly remembers that they forgot about Gliscor. Far away and close to tears, Gliscor continues its slow and lumbering journey back to the cabin.