Cotton Spore lowers the target's Speed stat by two stat levels. It will fail if the target's Speed stat has reached a stat level of -six or a value of 1, if the target has a Substitute, or is under the effect of Mist.
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| colspan="6" | Bold indicates a Pokémon which gets STAB from this move. Italic indicates a Pokémon whose evolution gets STAB from this move. *Indicates Pokémon that can only learn the move through chain breeding.
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| colspan="6" | Bold indicates a Pokémon which gets STAB from this move. Italic indicates a Pokémon whose evolution gets STAB from this move. *Indicates Pokémon that can only learn the move through chain breeding.
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