While the player has a Black or White Kyurem, the DNA Splicers be used to separate White Kyurem or Black Kyurem into Kyurem and the original Reshiram or Zekrom. All properties of the Reshiram or Zekrom will be retained.
The DNA Splicers first appeared in PS543, where Blake revealed that he had had them ever since he was a little child, not knowing how he got them. After Colress managed to make Zinzolin spill out his information regarding Kyurem's Absofusion, he relayed this information to Ghetsis, who had Kyurem call out to the DNA Splicers, causing them and Blake, who was trying to hold on to them, to fly up towards Kyurem. The item's energy eventually repelled Blake from it, and once Ghetsis ordered Kyurem to absorb N's Zekrom, Kyurem absorbed the DNA Splicers and forced Zekrom to turn into the Dark Stone, which it used to transform itself into Black Kyurem.