May's Skitty (Japanese: ハルカのエネコ Haruka's Eneco) was the third Pokémon caught by May during her travels through Hoenn. It was caught on Route 111. Its voice actress in both English and Japanese is 林原めぐみ Megumi Hayashibara.
Skitty made its debut in I Feel Skitty. Torchic wandered off during a training session and met a sick Skitty who would not eat or battle. Brock suggested they take it to a Pokémon Aromatherapy Center, where it was revealed that Skitty had wandered in the desert so long, it lost its sense of smell. Skitty recovered after it was sprayed with some medicine. Team Rocket then kidnapped Skitty because Jessie wanted it for herself. However, Meowth fell in love with Skitty and tried to help Skitty escape. Eventually, May and Jessie had a Pokémon battle with their Beautifly and Dustox to decide who would get Skitty; May proved victorious.
Skitty has a very cute and charming personality. Skitty is always cheerful, and loves to play with mops, string, and its own tail. Skitty can be a bit ditzy at times, though.
Apparently, Skitty in general are distantly related to Zangoose, as May's Skitty shares that species' dislike of Seviper, although this dislike is not as strong as that felt by a Zangoose.
When Skitty was first caught, during a few episodes it let itself out of its Poké Ball in the same way that Misty's Psyduck and Jessie's Wobbuffet do.