Multiple Weedle debuted in Challenge of the Samurai, where Ash was very close to catching one. He used his newly caught Pidgeotto to battle it, which resulted in Weedle being knocked unconscious. However, when Ash was about to throw his Poké Ball, Samurai came up and asked Ash if he was a Trainer from Pallet Town. This distracted Ash from catching Weedle, allowing it to escape. This same Weedle later warned its kind, and together, they tried to avenge its attempted capture by attacking his friends.
In The Bug Stops Here, Casey caught a Weedle during the Bug-Catching Contest, and later released it in accordance with the Contest rules.
A Weedle appeared in The Kangaskhan Kid.
In The Ultimate Test, a Trainer allowed Todd to photograph his Weedle. Due to a coloring error, this Weedle was colored green like a Caterpie. Generation II revealed that Shiny Weedle are green as well.
In Mewtwo Strikes Back, a Trainer's Weedle was defeated by Mewtwo while it was serving for Giovanni.
In In the Pink, multiple pink Weedle were residents of Pinkan Island.
In Tracey Gets Bugged, a Weedle was one of the Bug-type Pokémon on Murcott Island.
A wild Weedle appeared in Pikachu's Rescue Adventure.
In Illusion Confusion!, a Weedle was one of the illusions created by a group of Haunter and Gengar.
In For Crying Out Loud, multiple Weedle were accidentally soaked by Wilhomena's Marill.
In Gettin' The Bugs Out, multiple Weedle were residents of Azalea Gym. They assisted in tying Team Rocket up with silk.
Multiple Weedle appeared in Celebi: The Voice of the Forest.
In Got Miltank?, a Weedle was an inhabitant of a Pokémon-exclusive oasis.
In For Ho-Oh the Bells Toll!, multiple Weedle protected the Tin Tower after Team Rocket stole the Crystal Bells on the top floor.
In Talkin' 'Bout an Evolution, a Weedle fell sick due to Team Rocket's experiments.
In the banned episode EP250, a Weedle was in a forest outside the Ice Cave.
A Weedle appeared in All in a Day's Wurmple.
In Gonna Rule The School!, the Pokémon Trainers' School lent a Weedle to the school's underage students for use in lessons.
A Weedle appeared in Destiny Deoxys.
In The Saffron Con, a Coordinator's Weedle was stolen by Team Rocket. After being returned, it competed in the Saffron City Pokémon Contest in the next episode.
A Weedle appeared in The Green Guardian.
Two Weedle appeared in Three Jynx and a Baby!.
Two Weedle appeared in Talking a Good Game!.
In Once More With Reeling!, a Coordinator's Weedle participated in the Terracotta Contest.
A Weedle appeared in Following A Maiden's Voyage!.
In One Big Happiny Family!, a Weedle was healed by Nurse Joy after being injured.
A Weedle appeared in Kalos, Where Dreams and Adventures Begin!.
A Weedle living in Professor Sycamore's lab appeared in Lumiose City Pursuit!, Mega-Mega Meowth Madness!, Day Three Blockbusters!, and Battling With a Clean Slate!; as well as in a flashback in Garchomp's Mega Bond!.
A Weedle appeared in An Appetite for Battle!.
A Weedle appeared in a flashback in A Watershed Moment!.
A Weedle appeared in a flashback in Seeing the Forest for the Trees!.
Two Weedle appeared in I Choose You!.
In Mewtwo Strikes Back—Evolution, a Trainer at Old Shore Wharf was seen with a Weedle.
A Weedle appeared in a flashback in Enter Pikachu!.
In Working My Way Back to Mew!, Goh caught a Weedle. It has since made further appearances in Pokémon Journeys: The Series.
A Trainer's Weedle appeared in Caring for a Mystery!.
Two Weedle appeared in Trade, Borrow, and Steal!, with one under the ownership of a Trainer and the other being wild.
A Trainer's Weedle appeared in Crowning the Chow Crusher!.
A Weedle appeared in This Could be the Start of Something Big!.
A Weedle appeared in The Rainbow and the Pokémon Master!.
Two Weedle appeared in The Treasure After the Storm!. They reappeared in Found You, Fuecoco!, where they helped repair the damage to the Brave Olivine.
||Weedle. The stinger on this Pokémon's head guarantees that any attacker will get the point right where it hurts.
In File 1: Red, a Weedle was one of the Pokémon seen in Professor Oak's introduction.
In File 3: Giovanni, a Weedle was at Silph Co.
A Weedle appeared in Wait for Me, Magikarp!.