→Personality and characteristics
This Mewtwo is portrayed as a benevolent figure despite its mistrust of humans, much like both Mewtwo in the anime series after their character development. While mostly viewed by Tim and Pikachu as a dangerous, malevolent figure prior to meeting it, Mewtwo is in fact a protector of both humans and Pokémon, able to use its abilities to save the lives of others as it watches over them.
This Mewtwo differs from previous depictions of the character in two ways. The first is that it possesses the unique ability to transfer the minds of humans into Pokémon. The second is that it speaks with an androgynous "fused" telepathic voice provided by a male and a female voice actor, although it is referred to with male pronouns throughout the movie; however, when Howard's mind is transferred into Mewtwo, it speaks non-telepathically with his voice.