- Route 5 in Kanto, stretching between Cerulean City and Saffron City.
- Route 5 in Unova, stretching between Nimbasa City and the Driftveil Drawbridge.
- Route 5 in Kalos, stretching between Lumiose City and Camphrier Town.
- Route 5 in Alola, stretching between Paniola Ranch and Brooklet Hill on Akala Island.
- Route 5 in Galar, stretching between Turffield and Hulbury.