In the core series games
If held by a Lopunny, allows it to Mega Evolve into Mega Lopunny if its Trainer has a Key Stone. Each Trainer can only Mega Evolve one Pokémon per battle.
Unaffected by item negating effects (such as Embargo and Klutz). Item manipulating effects (such as Trick and Fling) cannot give Lopunny a Lopunnite or remove a Lopunnite from Lopunny.
Outside of battle
If held by a Lopunny, allows it to Mega Evolve into Mega Lopunny when it performs a Spectacular Talent during a Pokémon Contest Spectacular while its Trainer has a Key Stone. Lopunny will remain a Mega Lopunny until the Talent Round ends.
Pokémon holding Lopunnite in Pokémon Omega Ruby and Alpha Sapphire cannot be traded to Pokémon X and Y.
| One of a variety of mysterious Mega Stones. Have Lopunny hold it, and this stone will enable it to Mega Evolve during battle.
In spin-off games
|| This section is incomplete.|
Please feel free to edit this section to add missing information and complete it.
In Pokémon Shuffle, the Lopunnite allows the player to Mega Evolve Lopunny.
The player can obtain the Lopunnite by defeating Mega Lopunny in Stage 60 found on Rainbow Park.
The Lopunnite enables the following Mega Evolution:
|| Mega Lopunny
|| Erases all Pokémon five rows above and five rows below.
In other languages
|| 長耳兔進化石 Chèuhngyíhtou Jeunfa Sehk
|| 長耳兔進化石 / 长耳兔进化石 Cháng'ěrtù Jìnhuà Shí
|| 이어롭나이트 Ieoropnite