The Fuego Ironworks was first mentioned in Double Team Turnover!, where Mars reported that the research on the Veilstone meteorites that was being conducted there had been completed, and that the Red Chain project was nearing completion.
Unlike in the games, the Fuego Ironworks in the anime is abandoned and shut down due to pollution. They have been infiltrated by Team Galactic and reactivated secretly to experiment on the Red Chain and Veilstone meteorites.
Fuego Ironworks first appeared in Winning Over Wingull, where Pearl arrived there by accident after getting lost from his intended route to Lake Valor. After arriving, he was reunited with the Luxray that he had encountered several weeks earlier as a Luxio. Hearing voices from within the facility, Pearl rushed in to find Mr. Fuego, who revealed that Team Galactic had used the facility to produce the parts they required for the Galactic Bomb. After defeating the Pokémon that Team Galactic had left behind to guard the facility, Pearl asked Mr. Fuego for a list of parts that the villainous team had ordered.
In Cautious Clefairy, Mr. Fuego gave Pearl the list of ordered parts, which, to Pearl's confusion, revealed that Team Galactic was only building one Galactic Bomb, despite their goal being to capture all three lake guardians. He then offered to deliver some bolts and nuts to Rad Rickshaw in Eterna City in order to ask the bike shop owner why Team Galactic had held him captive earlier.
Fuego is the Spanish word for fire. Its Japanese name refers to 蹈鞴 tatara, foot bellows.