Charla belongs to Liza, who maintains the Valley. When Ash and his friends were going through the Valley, they had the opportunity to meet Charla. Charla is Liza's only Pokémon, and her greatest partner, seeing as she travels with her to places outside the valley. Charla was also the only non-wild Pokémon in the valley when Ash and his friends met her.
Charla made a brief cameo appearance in Spell of the Unown: Entei with Liza and other Charizard from the Charicific Valley. She and Liza were watching a live news report about the incident in Greenfield.
Charla was considered to be Liza's most trusted Pokémon out of the other Charizard in the Charicific Valley. During her debut episode, Charla had very little trouble in showing her flying skills in contrast to Ash's Charizard when they first arrived in the Valley. Charla started to bond with Ash's Charizard overtime during its stay at the Valley.
A † shows that the move was used recently, unless all moves fit this case or there are fewer than five known moves.
Charla's Japanese name, リサ Lisa, comes from Charizard's Japanese name, リザードン Lizardon, and is also a girl's name. Likewise, her English name is a portmanteau of Carla, a girl's name, and Char, part of the name of all of the members of the Charmander evolution family.
In her first appearance, she was much larger than Ash's Charizard. The next time the two were seen, she was the same size as it.