To play Berry Crush, the player must repeatedly press the 'A' button as fast as possible. Though similar to the Berry Blender, this game makes Berry Powder rather than Pokéblocks, as these have no use in the Kantoregion.
After the Berries have been crushed, the player will get some powder. This can be traded for certain items. The powder is stored in the Powder Jar, which can be obtained from an old man in a house in Cerulean CityFRLG or from a woman in the Slateport City outdoor marketE. These characters will also give away certain items depending on the amount of powder that the player has.
Aside from direct trading, this minigame is the only way to obtain herbal medicine in Pokémon FireRed and LeafGreen.