Vespiquen are bee-like Pokémon with yellow and black striped abdomen resembling an elegant ballroom gown. On the underside of the expansive abdomen are honeycomb-like cells that serve as a nest for baby Combee. It does appear, however, that they have a slender, more insect-like abdomen in the centermost cell, which is inconspicuous as the ‘skirt’ usually obstructs the view of it. Vespiquen have black, skinny arms with two orange claws and fly with a pair of relatively small wings on their orange shoulders. Their yellow upper bodies are a nearly perfect sphere and their waists are black and slender. Vespiquen's orange faces have intimidating, red eyes, oversized, yellow, protruding mandibles, and a red gem on their forehead that has grown significantly since being a Combee. The top portion of the head is similar to a headpiece of sorts with yellow and black horn-like projections, resembling a hairstyle historically favored by early medieval-period English queens.
Vespiquen is a female-only species with no male counterpart.
Vespiquen have three separate signature moves which are reportedly controlled by its pheromones, that involve summoning a swarm of baby Combee, which are stored in the honeycomb-like lower abdomen. One is for attacking, the second is for defending and the third is for recovering. The red gem on their forehead (which was developed from the small red dot on female Combee) allows them to use the move Power Gem.
Vespiquen are queens of hives of Combee, controlling it and protecting it, as well as giving birth to young Combee. A Vespiquen is far more powerful than her followers, and will only take action if her Combee are unable to protect the hive. If outsiders prove themselves to the Vespiquen by defending her hive, she may repay their acts of kindness with a reward.
Vespiquen live in huge hives in the forests with their Combee followers.