Pain Split adds the current HP of the user and target Pokémon. It then divides this value by two and sets the HP of both Pokémon to the result. If the new value is higher than the maximum HP of either Pokémon, that Pokémon will have its HP set to that maximum.
Template:Breedlist
|-
| style="background: #FFF; font-family:monospace,monospace" | 0109
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Koffing
| colspan="2" style="background:#9141CB; text-align: center;" | Poison
| style="background: #FFF" | Misdreavus
|-
| colspan="6" | Bold indicates a Pokémon which gets STAB from this move. Italic indicates a Pokémon whose evolution gets STAB from this move. *Indicates Pokémon that can only learn the move through chain breeding.
|}
|}
Bold indicates a Pokémon which gets STAB from this move. Italic indicates a Pokémon whose evolution or alternate form gets STAB from this move.
By breeding
Template:Breedlist
|-
| style="background: #FFF; font-family:monospace,monospace" | 0109
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Koffing
| colspan="2" style="background:#9141CB; text-align: center;" | Poison
| style="background: #FFF" | Misdreavus Gulpin, Swalot Duskull, Dusclops
|-
| style="background: #FFF; font-family:monospace,monospace" | 0316
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Gulpin
| colspan="2" style="background:#9141CB; text-align: center;" | Poison
| style="background: #FFF" | Koffing, Weezing Misdreavus Duskull, Dusclops
|-
| style="background: #FFF; font-family:monospace,monospace" | 0355
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Duskull
| colspan="2" style="background:#704170; text-align: center;" | Ghost
| style="background: #FFF" | Koffing, Weezing Misdreavus Gulpin, Swalot
|-
| colspan="6" | Bold indicates a Pokémon which gets STAB from this move. Italic indicates a Pokémon whose evolution gets STAB from this move. *Indicates Pokémon that can only learn the move through chain breeding.
|}
|}
Template:Breedlist
|-
| style="background: #FFF; font-family:monospace,monospace" | 0109
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Koffing
| colspan="2" style="background:#9141CB; text-align: center;" | Poison
| style="background: #FFF" | Misdreavus, Mismagius Gulpin, Swalot Duskull, Dusclops, Dusknoir Spiritomb
|-
| style="background: #FFF; font-family:monospace,monospace" | 0316
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Gulpin
| colspan="2" style="background:#9141CB; text-align: center;" | Poison
| style="background: #FFF" | Koffing, Weezing Misdreavus, Mismagius Duskull, Dusclops, Dusknoir Spiritomb
|-
| style="background: #FFF; font-family:monospace,monospace" | 0355
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Duskull
| colspan="2" style="background:#704170; text-align: center;" | Ghost
| style="background: #FFF" | Koffing, Weezing Misdreavus, Mismagius Gulpin, Swalot Spiritomb
|-
| style="background: #FFF; font-family:monospace,monospace" | 0442
| style="background: #FFF; text-align: center;" |
| style="background: #FFF" | Spiritomb
| colspan="1" style="background:#704170; text-align: center;" | Ghost || style="background:#624D4E" align="center" colspan="1" rowspan="1" | Dark
| style="background: #FFF" | Koffing, Weezing Misdreavus, Mismagius Gulpin, Swalot Duskull, Dusclops, Dusknoir
|-
| colspan="6" | Bold indicates a Pokémon which gets STAB from this move. Italic indicates a Pokémon whose evolution gets STAB from this move. *Indicates Pokémon that can only learn the move through chain breeding.
|}
|}