Karena, alongside her granddaughter Daniela, is the owner of a Day Care close to Nacrene City. When the children had rebelled because of a Trubbish they were not allowed to keep it, so Karena tried to help. She took Ash, Iris and Cilan to her Day Care and told them what happened.
In the end, she gave Ash a Pokémon Egg for all the help he did.
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